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Nafamostat mesylate (INN), a synthetic serine protease inhibitor, it is a short-acting anticoagulant,and is also used for the treatment of pancreatitis. It also has some potential antiviral and anti-cancer properties.Nafamostat is a fast-acting proteolytic inhibitor and used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin.The mechanism of action of Nafamostat is as a slow tight-binding substrate, trapping the target protein in the acyl-enzyme intermediate form, resulting in apparent observed inhibition.
CAS:82956-11-4
Molecular Formula:C21H25N5O8S2
Qualifications:GMP Evaluate Report
File:MOA DMF Stability data
Standard:JP
Nafamostat mesylate (INN), a synthetic serine protease inhibitor, it is a short-acting anticoagulant,and is also used for the treatment of pancreatitis. It also has some potential antiviral and anti-cancer properties.Nafamostat is a fast-acting proteolytic inhibitor and used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin.The mechanism of action of Nafamostat is as a slow tight-binding substrate, trapping the target protein in the acyl-enzyme intermediate form, resulting in apparent observed inhibition.
CAS:82956-11-4
Molecular Formula:C21H25N5O8S2
Qualifications:GMP Evaluate Report
File:MOA DMF Stability data
Standard:JP