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Tegoprazan works as a potassium-competitive acid blocker that is potent and highly selective.Its mechanism of action is different from that of the proton-pump inhibitors as this drug does not require conversion into an active form and can directly inhibit H+/K+‐ATPase in a reversible and K+‐competitive way.This is because it is an acid-resistant weak base with the ability to remain in the highly acidic canaliculi of gastric parietal cells.
CAS:942195-55-3
Molecular Formula:C20H19F2N3O3
Qualifications:GMP Evaluate Report/ KDMF
File:MOA DMF
Standard:In house
Tegoprazan works as a potassium-competitive acid blocker that is potent and highly selective.Its mechanism of action is different from that of the proton-pump inhibitors as this drug does not require conversion into an active form and can directly inhibit H+/K+‐ATPase in a reversible and K+‐competitive way.This is because it is an acid-resistant weak base with the ability to remain in the highly acidic canaliculi of gastric parietal cells.
CAS:942195-55-3
Molecular Formula:C20H19F2N3O3
Qualifications:GMP Evaluate Report/ KDMF
File:MOA DMF
Standard:In house